Relieving Spasticity to Revitalize Lives
Drinking a cup of coffee. Going for a leisurely walk. Opening the front door to greet a neighbor. These are among the countless, simple and common elements that make up the fabric of our daily lives. But for people with muscle spasticity, an abnormal increase in muscle tone or stiffness that interferes with movement, physical function and speech, these everyday tasks represent an extremely difficult endurance test with a finish line that is out of reach.
The High Cost of Spasticity:
The socio-economic cost of stroke survivors with spasticity is four-times higher than for those who live without spasticity.
Source: Lundström et al. Stroke 2010 Feb; 41(2): 319-24
Spasticity is a serious life-long consequence of traumatic injuries, leaving the nervous system unable to send relaxation signals to the contracted muscles. Spasticity, which can be chronic and progressive, is associated with common conditions, including cerebral palsy, stroke, head trauma, multiple sclerosis and spinal cord injury. Depending on the nature of the injury, spasticity can be global or localized to the upper body, lower body or right/left side of the body.
The burden of spasticity extends from its disabling constraints on independent physical function to its economic impact, which includes high cost to the individual and the health system due to the condition’s devastating effects and associated morbidity.
Elevating the Standard-of-Care
At Motric Bio, we’re focused on applying a novel scientific approach to the treatment of spasticity to relieve the burden of this debilitating condition for millions and restore movement and function for a better quality of everyday life.
The important work we are pursuing is taking place against a backdrop of a standard of care that is insufficient in addressing patients’ needs. Current treatment options for spasticity have low efficacy, are poorly tolerated and are often administered invasively to minimize side effects.
We’re aiming to elevate the treatment of spasticity through a novel approach that directly targets the contractile effector protein in muscle to deliver therapeutic muscle relaxation without cardiac or nervous system side effects.